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Online/Distance Resources for Nursing Students

Levels of Evidence

 

Tips for Weighing the Evidence:

  • Research with a control group (no intervention) and an experimental group is more reliable than research without. 
  • Research that is blinded—where the researchers don't know who is in which group—is better able to prove an effect than unblinded studies.
  • Because statistical flukes can happen, meta-analyses and systematic reviews from respected groups like Cochrane and JBI, which take a structured look at the existing research about a topic, are best able to reach a conclusion on how complete or established a scientific position is.
  • Responses matter. Scientific publishing is a conversation; papers cite each other to agree or disagree. Collecting articles that refer to each other gives you a better picture of your topic. 

When you start researching you will encounter many different types of evidence such as systematic reviews, randomized controlled trials, clinical guidelines and opinion articles.  These different resources will not all have the same "weight" in terms of reliability and trustworthiness.  

Evidence Level hierarchies are systems used to rank evidence according to certain criteria. There are many hierarchies, including the examples on this page.

Source: Hopp, L., & Rittenmeyer, L. (2012). Introduction to evidence-based practice: A practical guide for nursing. Philadelphia: F.A. Davis.


Click to open a window with more information. ANIMAL & LAB (IN VITRO) NON-HUMAN, PRELIMINARY NO DESIGN CASE SERIES CASE REPORTSEXPERT OPINIONS RETROSPECTIVE CASE CONTROLSTUDIES PROSPECTIVE COHORTSTUDIES PROSPECTIVE RANDOMIZEDCONTROLLEDTRIALS META-ANALYSESSYSTEMATIC REVIEWS CLINICAL PRACTICEGUIDELINES OBSERVATIONALRESEARCH SECONDARY STUDIES PRIMARY RESEARCH

What's NOT in the Included in the Levels of Evidence?

There are some types of sources you may encounter that aren't included in the Levels of Evidence.

Informational (non-experimental) sources may be useful for your understanding but should not be cited as scientific evidence.

Examples include: Informative articles, trade journal, magazine, and news articles, blogs, and popular sites such as Wikipedia.

  • These types of sources do not reflect primary research, nor are they an expert review of primary research the way clinical practice guidelines or systematic reviews are.
  • They may refer to or summarize research articles. Locate the research article rather than cite an author's summary of it. Some informational sources will include links to or citations for the original sources. 

Content adapted with permission from Grand Canyon University Library: https://libguides.gcu.edu/EvaluatingSources

Recommended Evidence by PICO Question Type

Therapy/Intervention

Systematic Reviews or Meta-Analysis
Randomized Controlled Trials
Clinical Practice Guidelines
Nonrandomized Controlled Trials
Cohort Study or Case-Control Studies
Meta-Synthesis of Qualitative or Descriptive Studies
Qualitative or Descriptive Studies
Expert Opinion

Diagnosis, Prognosis/Prediction

Synthesis of Cohort Study or Case-Control Studies
Single Cohort Study or Case-Control Studies
Meta-Synthesis of Qualitative or Descriptive Studies
Single Qualitative or Descriptive Studies
Expert Opinion

Meaning

Meta-synthesis of Qualitative Studies
Cohort Studies
Single Qualitative studies
Synthesis of Descriptive Studies
Single Descriptive Studies
Expert Opinion

Prevention

Randomized Controlled Trials
Cohort Studies
Case Control
Case Series

Economic Analysis

Economic Analysis